Molecular MR imaging of fibrosis in a mouse model of pancreatic cancer
Abstract Fibrosis with excessive amounts of type I collagen is a hallmark of many solid tumours, and fibrosis velgen vff 12 is a promising target in cancer therapy, but tools for its non-invasive quantification are missing.Here we used magnetic resonance imaging with a gadolinium-based probe targeted to type I collagen (EP-3533) to image and quanti